Use an interface that is split into panes.
This interface is more user-friendly and attractive, but requires a web browser that supports 'frames' and 'cookies'. If you don't recognize either term then you most likely have a browser that supports them.
Use a single-pane interface.
For old or 'thin' web browsers. More cumbersome to use.
Use a totally text-based interface.
Designed for very old or very 'thin' web browsers like PDA's or cell phones, or for extremely slow network connections. Very ugly, but very practical. This interface will work just about anywhere, it just won't necessarily look good doing it.
Don't cache output.
Check here to set QuickPop to mark all output pages as expired so that they will not be cached, for increased security and privacy. (Some web browsers may not honor page expiration directives.)